Adjust the amount and type of flush to avoid volume and/or sodium overload in pediatric patients.įor cardiac output studies, administer via the cardiac catheter.
Immediately after indocyanine green injection, switch the access on the stopcock and flush the line with 10 mL of 0.9% Sodium Chloride Injection. The normal percentage disappearance rate in healthy subjects is 18% to 24% per minute.įor visualization of vessels, blood flow, and tissue perfusion, administer via a central or peripheral venous line using a 3-way stopcock attached to an injection port on the infusion line. Changing concentrations of indocyanine green can be monitored by ear densitometry or by obtaining blood specimens at timed intervals (i.e., photometric method). Study the patient in a fasting, basal state. Indocyanine green is administered as a rapid IV bolus.įor hepatic function studies, administer into the lumen of an arm vein as rapidly as possible, without allowing the dye to escape outside the vein. The dye is stable in whole blood and plasma, so samples obtained during testing may be read hours later. Storage: Indocyanine green is unstable in aqueous solution and must be used within 6 hours. The amount of Sterile Water for Injection to be used is determined by the procedure to be performed.įor hepatic function studies, dilute 25 mg indocyanine green with 5 mL of Sterile Water for Injection (5 mg/mL).įor visualization of vessels, blood flow, tissue perfusion, and extrahepatic biliary ducts, dilute 25 mg indocyanine green with 10 mL of Sterile Water for Injection (2.5 mg/mL).įor ophthalmic angiograms, dilute up to 40 mg indocyanine green with 2 mL of Sterile Water for Injection (up to 20 mg/mL).įor lymphatic mapping, dilute 25 mg indocyanine green with 20 mL of Sterile Water for Injection (1.25 mg/mL).ĭiscard the solution if the product precipitates. Under sterile conditions, dissolve the indocyanine green powder with Sterile Water for Injection.
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